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1

Buccal delivery of an α2-adrenergic receptor antagonist, atipamezole, in humans*

Huupponen, Risto, Karhuvaara, Sakari, Anttila, Markku, Vuorilehto, Lauri, Scheinin, Harry

Journal:

Clinical Pharmacology & Therapeutics

Year:

1995

Language:

english

File:

PDF, 544 KB

english, 1995

2

Influence of hydroxychloroquine on the bioavailability of oral metoprolol

Mika Somer, Jaana Kallio, Ullamari Pesonen, Kaija Pyykkö, Risto Huupponen, Mika Scheinin

Journal:

British Journal of Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 88 KB

english, 2000

3

Automatic analysis of electro-encephalogram sleep spindle frequency throughout the night

E. Huupponen, S. -L. Himanen, J. Hasan, A. Värri

Journal:

Medical and Biological Engineering and Computing

Year:

2003

Language:

english

File:

PDF, 690 KB

english, 2003

4

Pharmacokinetics of (deaminohydroxy)toremifene in humans: a new, selective estrogen-receptor modulator

M. W. DeGregorio, G. T. Wurz, T. L. Taras, R. U. Erkkola, K. H. Halonen, R. K. Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 122 KB

english, 2000

5

Computer program for automated sleep depth estimation

Antti Saastamoinen, Eero Huupponen, Alpo Värri, Joel Hasan, Sari-Leena Himanen

Journal:

Computer Methods and Programs in Biomedicine

Year:

2006

Language:

english

File:

PDF, 713 KB

english, 2006

6

Effect of Subchronic Metformin Treatment on Macronutrient Selection in Genetically Obese Zucker Rats

Juha Rouru, Risto Huupponen, Eriika Santti, Markku Koulu

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1993

Language:

english

File:

PDF, 363 KB

english, 1993

7

Nurse students' medication competence — An integrative review of the associated factors

Virpi Sulosaari, Satu Kajander, Maija Hupli, Risto Huupponen, Helena Leino-Kilpi

Journal:

Nurse Education Today

Year:

2012

Language:

english

File:

PDF, 870 KB

english, 2012

8

Effects of Diet and Simvastatin on Serum Lipids, Insulin, and Antioxidants in Hypercholesterolemic Men

Jula, Antti, Marniemi, Jukka, Huupponen, Risto, Virtanen, Arja, Rastas, Merja, Rönnemaa, Tapani

Journal:

JAMA The Journal of the American Medical Association

Year:

2002

Language:

english

File:

PDF, 133 KB

english, 2002

9

The zero-bias anomaly of point contacts with ferromagnetic Ni and with the heavy-fermion antiferromagnet CeAl 2

Gloos, Kurt, Huupponen, Jouko

Journal:

Journal of Physics Conference Series

Year:

2010

Language:

english

File:

PDF, 517 KB

english, 2010

10

Effect of the Benzodiazepine Derivative, Diazepam, on the Clonidine-Stimulated Human Growth Hormone Secretion

Koulu, Markku, Pihlajamaki, Kalevi, Huupponen, Risto

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1983

Language:

english

File:

PDF, 318 KB

english, 1983

11

The single dose pharmacokinetics and safety of deramciclane in healthy male volunteers

Harri Kanerva, Olavi Kilkku, Esa Heinonen, Antti Helminen, Juha Rouru, Simo Tarpila, Mika Scheinin, Risto Huupponen, Imre Klebovich, Sandor Drabant, Arto Urtti

Journal:

Biopharmaceutics & Drug Disposition

Year:

1999

Language:

english

File:

PDF, 201 KB

english, 1999

12

Intelligent methods for identifying respiratory cycle phases from tracheal sound signal during sleep

A. Kulkas, E. Huupponen, J. Virkkala, M. Tenhunen, A. Saastamoinen, E. Rauhala, S.-L. Himanen

Journal:

Computers in Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 314 KB

english, 2009

13

Determination of dominant simulated spindle frequency with different methods

Eero Huupponen, Wim De Clercq, Germán Gómez-Herrero, Antti Saastamoinen, Karen Egiazarian, Alpo Värri, Bart Vanrumste, Anneleen Vergult, Sabine Van Huffel, Wim Van Paesschen, Joel Hasan, Sari-Leena Hi

Journal:

Journal of Neuroscience Methods

Year:

2006

Language:

english

File:

PDF, 503 KB

english, 2006

14

Diffuse sleep spindles show similar frequency in central and frontopolar positions

E. Huupponen, A. Kulkas, M. Tenhunen, A. Saastamoinen, J. Hasan, S-L. Himanen

Journal:

Journal of Neuroscience Methods

Year:

2008

Language:

english

File:

PDF, 414 KB

english, 2008

15

Automatic detection of spiking events in EMFi sheet during sleep

Jarmo Alametsä, Esa Rauhala, Eero Huupponen, Antti Saastamoinen, Alpo Värri, Atte Joutsen, Joel Hasan, Sari-Leena Himanen

Journal:

Medical Engineering & Physics

Year:

2006

Language:

english

File:

PDF, 643 KB

english, 2006

16

Pharmacokinetics of finrozole (MPV-2213ad), a novel selective aromatase inhibitor, in healthy men

Outi Ahokoski, Kerttu Irjala, Mikko Taalikka, Pekka Manninen, Kaija Halonen, Lauri Kangas, Eeva Salminen, Risto Huupponen, Harry Scheinin

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 71 KB

english, 2001

17

Hormonal effects of MPV-2213ad, a new selective aromatase inhibitor, in healthy male subjects. A phase I study

Outi Ahokoski, Kerttu Irjala, Risto Huupponen, Kaija Halonen, Eeva Salminen, Harry Scheinin

Journal:

British Journal of Clinical Pharmacology

Year:

1998

Language:

english

File:

PDF, 84 KB

english, 1998

18

Dose linearity study of selegiline pharmacokinetics after oral administration: evidence for strong drug interaction with female sex steroids

Kari Laine, Markku Anttila, Antti Helminen, Hari Karnani, Risto Huupponen

Journal:

British Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 99 KB

english, 1999

19

Optimization of sigma amplitude threshold in sleep spindle detection

E. Huupponen, A. Värri, S.-L. Himanen, J. Hasan, M. Lehtokangas, J. Saarinen

Journal:

Journal of Sleep Research

Year:

2000

Language:

english

File:

PDF, 315 KB

english, 2000

20

2-[18F]fluoro-2-deoxy-d-glucose combined with microdialysis can be used for the comparison of tissue glucose metabolism in obese and lean rats

K. A. Virtanen, M. Haaparanta, T. Grönroos, J. Bergman, O. Solin, J. Rouru, P. Nuutila, R. Huupponen

Journal:

Diabetes, Obesity and Metabolism

Year:

2002

Language:

english

File:

PDF, 271 KB

english, 2002

21

Roles of chlorpropamide, alcohol and acetaldehyde in determining the chlorpropamide-alcohol flush

L. Groop, C. J. P. Eriksson, R. Huupponen, R. Ylikahri, R. Pelkonen

Journal:

Year:

1984

Language:

english

File:

PDF, 472 KB

english, 1984

22

HLA haplotypes in Type 1 (insulin-dependent) diabetes mellitus: molecular analysis of the HLA-DQ locus

P. J. Tienari, E. Tuomilehto-Wolf, J. Tuomilehto, L. Peltonen, H. K. Åkerblom, A. Fagerlund, M. Flittner, B. Gustafsson, A. Hakulinen, L. Herva, P. Hiltunen, T. Huhtamäki, N. P. Huttunen, T. Huupponen

Journal:

Year:

1992

Language:

english

File:

PDF, 1.07 MB

english, 1992

23

Effect of guar gum on glipizide absorption in man

R. Huupponen, S. Karhuvaara, P. Seppälä

Journal:

European Journal of Clinical Pharmacology

Year:

1985

Language:

english

File:

PDF, 325 KB

english, 1985

24

Severe hyponatremia caused by intranasal desmopressin for nocturnal enuresis

Jaana Kallio, Päivi Rautava, Risto Huupponen, Heikki Korvenranta

Journal:

Pediatric Nephrology

Year:

1994

Language:

english

File:

PDF, 143 KB

english, 1994

25

Apolipoprotein E phenotypes and plasma lipids in diabetic children and adolescents

M. K. Salo, R. Rantanen, T. Huupponen, T. Lehtimäki, H. Jokela

Journal:

European Journal of Pediatrics

Year:

1993

Language:

english

File:

PDF, 440 KB

english, 1993

26

Prevalence of debrisoquine oxidation phenotypes in glaucoma patients

L. Salminen, R. Lindberg, H. -R. Toivari, R. Huupponen, T. Kaila, E. Iisalo

Journal:

International Ophthalmology

Year:

1989

Language:

english

File:

PDF, 214 KB

english, 1989

27

Effect of doxazosin on insulin sensitivity in hypertensive non-insulin dependent diabetic patients

R. Huupponen, A. Lehtonen, M. Vähätalo

Journal:

European Journal of Clinical Pharmacology

Year:

1992

Language:

english

File:

PDF, 643 KB

english, 1992

28

The relationship between debrisoquine oxidation phenotype and the pharmacokinetics of chlorpropamide

J. Kallio, R. Huupponen, K. Pyykkö

Journal:

European Journal of Clinical Pharmacology

Year:

1990

Language:

english

File:

PDF, 267 KB

english, 1990

29

Heavy users of non-steroidal anti-inflammatory drugs: a nationwide prescription database study in Finland

Arja Helin-Salmivaara, Timo Klaukka, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 235 KB

english, 2003

30

Effect of the novel anxiolytic drug deramciclane on the pharmacokinetics and pharmacodynamics of the CYP3A4 probe drug buspirone

Kari Laine, Outi Ahokoski, Risto Huupponen, Jutta Hänninen, Sanna Palovaara, Jori Ruuskanen, Harry Björklund, Markku Anttila, Juha Rouru

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 222 KB

english, 2003

31

Frequent prescribing of drugs with potential gastrointestinal toxicity among continuous users of non-steroidal anti-inflammatory drugs

Arja Helin-Salmivaara, Risto Huupponen, Arja Virtanen, Jari Lammela, Timo Klaukka

Journal:

European Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 254 KB

english, 2005

32

Risk of serious upper gastrointestinal events with concurrent use of NSAIDs and SSRIs: a case-control study in the general population

Arja Helin-Salmivaara, Teppo Huttunen, Juha M. Grönroos, Timo Klaukka, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 117 KB

english, 2007

33

Reply to letter by Foster, van der Molen and de Jong-van den Berg

Pasi Lampela, Sirpa Hartikainen, Raimo Sulkava, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 44 KB

english, 2007

34

Selective prescribing of simvastatin and atorvastatin by patient characteristics at treatment initiation over a 7-year period in Finland

Heli Halava, Arja Helin-Salmivaara, Jouni Junnila, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 132 KB

english, 2009

35

Protopathic bias in observational studies on statin effectiveness

Maarit Jaana Korhonen, Risto Huupponen, Päivi Ruokoniemi, Arja Helin-Salmivaara

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 64 KB

english, 2009

36

Dynamics of long-term statin therapy

Maarit Jaana Korhonen, Arja Helin-Salmivaara, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 228 KB

english, 2011

37

Suboptimal use of statins at treatment initiation

Vesa Kiviniemi, Piia Peura, Arja Helin-Salmivaara, Jaana E. Martikainen, Juha Hartikainen, Risto Huupponen, Maarit Jaana Korhonen

Journal:

European Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 72 KB

english, 2011

38

A medication database – a tool for detecting drug interactions in hospital

P. E. Grönroos, K. M. Irjala, R. K. Huupponen, H. Scheinin, J. Forsström, J. J. Forsström

Journal:

European Journal of Clinical Pharmacology

Year:

1997

Language:

english

File:

PDF, 125 KB

english, 1997

39

Aqueous humour concentration and the intraocular pressure-lowering effect of topical betaxolol before cataract surgery

E. Vainio-Jylhä, M.-L. Vuori, T. Kaila, R. Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

1998

Language:

english

File:

PDF, 134 KB

english, 1998

40

A double-blind study of MPV-2213ad, a novel aromatase inhibitor, in healthy male subjects

O. Ahokoski, K. Irjala, S. Huhtala, E. Salminen, H. Scheinin, R. Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 198 KB

english, 1999

41

Pharmacokinetics of oral entacapone after frequent multiple dosing and effects on levodopa disposition

J. Rouru, A. Gordin, R. Huupponen, S. Huhtala, E. Savontaus, K. Korpela, K. Reinikainen, M. Scheinin

Journal:

European Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 114 KB

english, 1999

42

Anteroposterior Difference in EEG Sleep Depth Measure is Reduced in Apnea Patients

Eero Huupponen, Antti Saastamoinen, Atte Joutsen, Jussi Virkkala, Jarmo Alametsä, Joel Hasan, Alpo Värri, Sari-Leena Himanen

Journal:

Journal of Medical Systems

Year:

2005

Language:

english

File:

PDF, 221 KB

english, 2005

43

Identification of Deep Sleep and Awake with Computational EEG Measures

Eero Huupponen, Antti Kulkas, Antti Saastamoinen, Mirja Tenhunen, Sari-Leena Himanen

Journal:

Journal of Medical Systems

Year:

2011

Language:

english

File:

PDF, 234 KB

english, 2011

44

Detection of compressed tracheal sound patterns with large amplitude variation during sleep

A. Kulkas, E. Rauhala, E. Huupponen, J. Virkkala, M. Tenhunen, A. Saastamoinen, S-L. Himanen

Journal:

Medical and Biological Engineering and Computing

Year:

2008

Language:

english

File:

PDF, 421 KB

english, 2008

45

Improved computational fronto-central sleep depth parameters show differences between apnea patients and control subjects

E. Huupponen, T. Saunamäki, A. Saastamoinen, A. Kulkas, M. Tenhunen, S.-L. Himanen

Journal:

Medical and Biological Engineering and Computing

Year:

2009

Language:

english

File:

PDF, 499 KB

english, 2009

46

New tracheal sound feature for apnoea analysis

A. Kulkas, E. Huupponen, J. Virkkala, M. Tenhunen, A. Saastamoinen, E. Rauhala, S.-L. Himanen

Journal:

Medical and Biological Engineering and Computing

Year:

2009

Language:

english

File:

PDF, 516 KB

english, 2009

47

Determination of metformin in plasma by high-performance liquid chromatography

R. Huupponen, P. Ojala-Karlsson, J. Rouru, M. Koulu

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1992

Language:

english

File:

PDF, 196 KB

english, 1992

48

Topographic differences in mean computational sleep depth between healthy controls and obstructive sleep apnoea patients

Antti Saastamoinen, Hannu Oja, Eero Huupponen, Alpo Värri, Joel Hasan, Sari-Leena Himanen

Journal:

Journal of Neuroscience Methods

Year:

2006

Language:

english

File:

PDF, 162 KB

english, 2006

49

Systematic performance evaluation of a continuous-scale sleep depth measure

Antti Saastamoinen, Eero Huupponen, Alpo Värri, Joel Hasan, Sari-Leena Himanen

Journal:

Medical Engineering & Physics

Year:

2007

Language:

english

File:

PDF, 1.40 MB

english, 2007

50

Shift of statin use towards the elderly in 1995−2005: a nation-wide register study in Finland

Päivi Ruokoniemi, Arja Helin-Salmivaara, Timo Klaukka, Pertti J. Neuvonen, Risto Huupponen

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 561 KB

english, 2008

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